International Managment Essay Example | Topics and Well Written Essays - 3000 words

International Managment - Essay Example Zen meditation is all about focusing, inward, looking at yourself, your own soul and become one with oneself. This experience is a whole new philosophy that anyone can apply to any aspect of one’s life. Zen art has shown me the way, the true way to wisdom and knowledge and I’m not going to stop at any demented or passive thought of abandoning the journey of my life enlightenment. Zen is not just about seeing things as they are; mountains as mountains and rivers as rivers, it is much more than that (Borup, 2008). The second activity worth mentioning is giving an insight to others about my own country, Saudi Arabia. This time, I analyse my country as an outsider and see it in a different light. And show what secrets it holds for the people who are unfamiliar with this land that was once nothing but desert cones. But now the world knows Saudi Arabia as one of the key players in the world energy sector. There is so much more to discover in Saudi Arabia other than deserts an d oil. There is only a little that the world knows about the people of Saudi Arabia, its culture, religion, food, the way people live and communicate with each other, and how recent developments have changed the life of Saudis. This is how it should be; people should recognize a country for its diversity and not for just a specific thing or two. A country is not its products, its natural resources but its people. Activity I: New Cultural Experience The Zen Meditation Impression It would be better to introduce Zen before delving into the details of its meditation. Zen is one of the many schools of Buddhists teachings, called Mahayana Buddhism (Zen.rinnou.net). China was the birthplace of this meditation but now this practice is world popular. Zen is the key to the great wisdom of Asia (Johnston, 2003), an inner art and â€Å"design of the Orient† (Reps & Senzaki, 1998, pp. 17-18). The art of Zen awakens the student to the art of formless (Merton, 1968, pp. 6-7), which also mea ns not pondering at the pointed finger but observing what is being pointed at (Johnson, 2000, pp. 21-22). I have joined the Sydney Zen Center in Annandale, NSW. I’ve attended two gatherings there or more than two hours each. It has turned out to be a great cultural experience for me. I have come to know about the Chinese Buddhist culture and how it resonates in the life of an individual. The Zen philosophy is all about attaining inner peace, also known as enlightenment. The main focus is developing an insight into the Buddhist teachings. So it is not merely reciting some verses, or visiting the temple, it is about applying the principles of Zen in one’s life and seeing how it creates a difference in the everyday living. The first lesson given by the teacher was to defeat duality. I later read in book that the most important lesson of Zen is not to be dualistic (Suzuki, 2010). The feelings I experienced were incredible, I have never felt an inward observation towards my soul. Zen is magical and whoever journey’s it finds whatever they seek (Arokiasamy, 2005). The feelings were mostly of calm and peacefulness as if eliminating the negative energy out of one’s mind and filling it with the pure white energy. This white energy also fills the mind and the eyes, and that is how one starts to feel and see the world differently. The calmness of this energy put me to a state of mind where I stopped resisting and fighting for useless objectives. After the meditation session was over I felt as if we all engage in many

Level 3 Childcare Education Essay Example for Free

Level 3 Childcare Education Essay Describe the initiatives which influence the provision of challenging environments for children (5 marks) There are different types of international, national and local initiatives which influence the provision of challenging environments for children. An example of an initiative is the Forest Schools. ‘A Forest School is an innovative educational approach to outdoor play and learning’ http://www. forestschools. om/what-happens-at-a-forest-school/ Forest schools can influence the provision of a challenging environment, as the teachers can take the children in small groups every week to the local woods to have a better understanding of the outdoor environment and it’s linked to the curriculum. By doing this it enables children to be able to be in a safe environment when exploring and having adventures so they can see what things they can do when they go into the woods next time. It can also help children with problems such as language problems as this allows them to speak about the experience they are having which can then be taken to the classroom and then it could be turned into a story to help the child. When going into the woods it helps to cater the behaviour for the problem children and it also teaches children when they can and can’t mess around. It also focuses on the fundamental aspect of the Forest School innovation educational approach. The Forest School provides ways for meeting learning objectives while developing practical life skills and encouraging child-initiated learning, which is observed and assessed. Lots of young children prefer to be outside than in the classroom environment because they can find it more exciting and they might pay more attention. Word Count- 240

Changing Marketing Strategies of Pharmaceutical Companies

Changing Marketing Strategies of Pharmaceutical Companies Abstract Pharmaceutical companies spend large sums of money in the time-consuming research and development of new drugs and the new classes of drugs. Each company marketing in the US seeks the possible payoff of staggering high profits which is possible on their patented medicines. Because of the lack of price regulation in the marketing environment in the United States, the United States has become a premium sales market targeted by all pharmaceutical companies. This explains the continued willingness of each pharmaceutical company to persist through the entire long process of idea, creation, development, testing, approval, marketing and distribution despite the high possibility of product failure. The pharmaceutical companies have had to additionally contend with more US federal FDA rules, regulation and oversight in the United States for the entire process before receiving clearance to start marketing their drug product. Other influences like HMOs and Social Security cap limits affect prof itability structure. Over the last fifty years newer marketing strategies by pharmaceutical companies on prescription drugs include a directive appeal to the end consumer to increase the odds of making corporate profits and a marketing focus on social and internet interaction. Introduction Pharmaceutical companies produce specialized medical drug material designed to fill a need. These pharmaceutical companies are usually multinational operations located in key countries around the globe. Many have grown to become complete facilities that attempt to do the entire spectrum of research, develop, test and finally market the subject drug in order to reap the whole benefits possible from the entire cycle (Kaitin, 2010). The pharmaceutical industry has shown over time that they have the capability to increase consumer perceived value with their unique drug products using their own successful plans for timely marketing. But because of these old and new factors causing cumulative hurtles, a new trend in marketing in the pharmaceutical industry is now to additionally market direct to the customer, for example: TV advertising spots showing a new superior drug product which has special features making it directly appealing to a consumer. Changes in basic marketing structure tacti cs will be evaluated for the key levels of pressure from these internal and external factors as these pharmaceutical companies seek to address continuing ongoing product failure rates, increasing US regulation and the ever present potential competition from others inside their own industry. This trend has been a natural development over the last hundred years or so. This is reasonable because the same research that produces one drug may produce an entire class of drugs for market. Confidentiality, control, patents and oversight give these pharmaceutical companies the oversight. It also allows each pharmaceutical company to keep maximum control of all their connected environments. And by controlling these the final marketing each company achieve continues the cycle of giving the most control over the drug for the marketing campaign. The drug industry often competes worldwide and on different economic levels but in some specific territorial markets like the United States, pricing structures are not preset by the government and therefore the free market sets its own competitive standards for pricing giving the possibility and most often the probability of higher drug prices with the resultant bigger profit level opportunities. However these are offset by rigorous structural standard guidelines set by the FDA that must be complied with for any drug sold or marketed to the US public. In the past, drug companies in United States, marketed to doctors, hospitals, nursing homes and sometimes middleman companies as transitional handlers of the newest product. Marketing drugs in the United states has now changed as developers are now targeting consumers directly through television spots, online advertising and in print ads. The direct appeal is to make the end point consumer aware of the name of the drug and its benefits. The object is to have the consumer become familiar with the trade name, ask for the drug directly from their doctor thus boosting the initial sales of the new product and creating a ready market. Industry History Marchetti Schellens (2007) outline the structures of development showing it to be complex and expensive. Not only does the potential class or specific drug have to be discovered or created, it has to show promise for certain illness or disease, then pharmaceutical research can proceed through certain phases. Pharmaceutical companies have a history of costly product failures. Generally theres three clinical phrases and all this can take upwards of 15 years to complete. Additionally the FDA has trended over the last decade to creating higher pressures against drug companies by not approving as many new drugs for marketing. The probability odds are that any specific drug in early clinical phase has only 8% chance or less of ever becoming public (Food and Drug Administration, 2006) (Kummar, 2007). In the United States the U.S. Food and Drug Administration (FDA) has sought to control the drugs available to Americans because of the number of tragedies that have resulted in birth defects o r deaths. The most highly publicized incident was in the mid-1960s and the drug was called thalidomide which for pregnant women often resulted in severe birth defects. As an end result of public outrage creating governmental pressures, the pharmaceutical companies are overseen at all levels and must now successful clinical trials. Lamb(1998) writes that testing protocols have been standardized and once clinical trials are completed there is a analysis period with the end result being an application to the FDA called an NDA ( new drug application) which contains all the technical information. Over the last forty years (1970s -2010) and now in 2011 differential forces are in opposition to the ends of pharmaceutical companies. Environmental and safety issues, new technologies, mergers and the rise of managed care and health maintenance organizations (HMOs) have all effectively changed the environment thats pharmaceutical companies operate in. additionally in 1997 the FDA changed regulations relating to the presentation of risk level. This action in the United States opened the door for pharmaceutical companies to directly market to the public .This freedom for the pharmaceutical companies is offset by the FDA still having oversight surveillance of the specific phases and clinical approval. The FDA must approve the drug. After the drug is marketed there is oversight for continued compliance by the pharmaceutical companies to ensure a low-level of side effects during marketing. Post approval by the FDA comes solely after this period (Silverman, 2011). Pharmaceutical company spending on marketing exceeds that spent on research.[3][22] In 2004 in Canada $1.7 billion a year was spent marketing drugs to physicians and in the United States $21 billion were spent in 2002.[4] In 2005 money spent on pharmaceutical marketing in the US was estimated at $29.9 billion with one estimate as high as $57 billion.[3] When the US number are broken down 56% was free samples, 25% was detailing of physicians, 12.5% was direct to consumer advertising, 4% on hospital detailing, and 2% on journal ads.[4] In the United States approximately $20 billion could be saved if generics were used instead of equivalent brand name products.[3] Although pharmaceutical companies have made large investments in marketing their products, overall promotional spending has been decreasing over the last few years, and declined by 10 percent from 2009 to 2010. Pharmaceutical companies are cutting back mostly in detailing and sampling, while spending in mailings and print advertising grew since last year.[23] Historical Marketing Pharmaceutical companies have employed various methods of marketing their products and this idea can be understood by the phrase â€Å"How would you like to be in an industry where your buyers are uninformed about your product and almost 100 per cent insensitive to its price?† (The Business Edge Consortium, 2010). For many decades this was true. Around the mid 80s this started to change â€Å"The result of these industry conditions was impressive profit growth through the middle of the 1980s. With significant barriers to entry, docile suppliers, powerless buyers, almost no threat of substitutes, and little rivalry, the pharmaceutical industry in the 1980s was just about as perfect an industry as one could imagine. Given its attractiveness, the industry attracted the attention of genetic and molecular biology scientists and the venture capital community, who saw its appeal and thought their revolutionary approaches to drug therapy could attract enough money to overcome the for midable entry barriers the industry enjoyed. Thus, as scientific advances in biotechnology took hold, numerous entrepreneurial companies like Genentech and Amgen were founded to commercialize new scientific breakthroughs. Genentech, the first biotech firm having commercial success, developed a protein that broke up blood clots. Amgens famous molecular biology used recombinant DNA to produce erythropoietin, a hormone that increases the supply of red blood cells in anaemic patients under treatment for cancer and other diseases. By 2000, erythropoietin was generating $2 billion in sales and another $3 billion in licensing revenue for Amgen. Both of these new entrants fared very well in this attractive industry:Genentech went public in 1980, and by 2001 its shares had appreciated 2700 per cent since its IPO. Amgen shares, first offered in 1983, soared more than 16,000 per cent. Starting in the mid-1980s, the barriers to enter the pharmaceutical industry began to show cracks. New legislation made it easier for generic drug companies to enter the market. In the USA, the 1984 Waxman-Hatch Act, which changed the rules for generic drug manufacturers, reduced the barriers to generic entry. Instead of having to prove the generic drugs safety and efficacy, the act required companies only to prove their formulas were equivalent to that of the brandname drug. The subsequent growth in generic drugs was profound. By 1996, generic drugs accounted for more than 40 per cent of pharmaceutical prescriptions. Aside from the influx of generics, the pharmaceutical companies also saw a wave of biotechnology competitors enter their industry Genentech, Amgen and many others suggesting that economies of scale meant less than they used to, and that barriers to entry, while still high in absolute terms, were dropping, thanks in part to the availability of venture capital. Further, the biotech companies new science-focused research model, known as rational drug design, stood the traditional approach to drug discovery on its head. These drug companies worked backwards from known disease biochemistry to identify or design chemical ‘keys to fit the biochemical ‘locks of that disease.† Traditionally they employed very effective strategies that includes educational sponsorship to cover the costs of continuing instruction for top medical personnel, sponsorship of articles in well-respected journal publications, providing free drugs samples to doctors and promotional gifts that include a corporate logo or specifics about a drug the idea behind the promotional marketing is to simply connect the new drug with an old medical symptom and encourage the writers of the prescription to fulfill the marketing cycle. Promantally pharmaceutical samples are still given out to doctors as a promotion and marketing tactic and it works (Alexander, Zhang Basu, 2008). A few generations ago these forms of marketing worked well for the pharmaceutical companies. However circumstances have changed. The FDA seeks to discourage the intimate connection between pharmaceutical companies and their pharmaceutical representatives is the connection to the doctors prescribing medicines, these days d octors see more patients and fewer pharmacy drug representatives, additionally there is a continuing trend by hospitals, doctors and pharmacies towards being conservative in their recommendations and prescriptions because of lawsuits of all kinds (Pharmaceutical Industry History, 2007). Medical drug malpractice suits in the US are rising. Fiscus (2008) writes that â€Å" In the United States, the growing use of DTC advertising has raised challenges to one of the strongest defenses available to drug manufacturers against failure to warn allegations in product liability suits for prescription drugs and medical devices: the learned intermediary doctrine. Under this doctrine, a manufacturer fulfills its duty to warn by adequately informing a learned intermediary, typically a physician.† Current Marketing .In 2010 the global pharmaceutical market is worth over 825 million with a large percentage of this comes from newer and mature drug products and there are over 100,000 health-related websites (The Business Edge Consortium, 2010). The statistics show that marketing by pharmaceutical companies is changing because of external pressures. There has been a dramatic rise in U.S. physicians routinely using d the web to check or research information making the relevance of digital promotion all the more important Pharmaceutical companies have risen to the changing challenge of Internet marketing and now promote and advertise doctor friendly physician and customer service online portals like PubMed, the U.S. National Library of Medicine, National, and Physicians Interactive (Kaitin, 2010). Pharmaceutical marketers are relying more on connecting digital medical information to their target audience through focused marketing, interactive social media campaigns, and cell and mobile linked advertising all targeted to connect to the 145 million + U.S. adults who go online for health answers . The old saying â€Å" time is money† is accurate in the case of pharmaceutical companies as it takes upwards of 15 years to develop a potential drug which only has a 8% probability of getting out of trials and going to market. Therefore it is a necessity to carefully control costs and expenses where possible. One major area of expense has been having marketing representatives which were costing out as high as15 to 20% of a pharmaceutical companies annual drug product revenues. As pharmaceutical company overall expenses and costs have additionally escalated over the last few generations there is a need to reduce expenses down where possible. So the switch from costly pharmaceutical representatives to cheaper graphic marketing is easily understood. Finkelstein (1997) wrote that Competitive and technological changes in the pharmaceutical industry-from powerful new drug chemistries to innovative RD partnerships and marketing plans-are reshaping the business strategies of many phar maceutical and biotechnology companies Given these cost pressures it is understandable that the pharmaceutical companies are looking for better ways to market their drugs. The newest strategy is now to promote what is known as marketing blockbuster medical drugs directly to the consumer public. The idea was to empower the consumer. Right now only the United States and New Zealand allow pharmaceutical products promoted by DTC (Pharmaceutical Drug Manufacturers, 2011). When an individual consumer requests information and the medicine by name by their Doctor some of the responsibility while also applying pressure on the doctor to prescribe the new medicine. Additionally both the small and large pharmaceutical companies are now using digital media to promote their products. From TV and cable to Internet ads consumers are constantly being made aware of the virtues and minor drawbacks of a number specific pharmaceutical drugs. The reasoning behind this strategy by the pharmaceutical companies is relatively simple, if they can promote their products and make its trade name and cure synonymous with the ongoing medical complaint in the publics mind, then they can create momentum utilizing the end customer. Another reason for doing this is to get any of their major blockbuster drugs to pay for the company costs for their other company made drugs sold in smaller volumes Another reason for marketing these blockbuster drugs as to make a success of these drugs synonymous with the company name creating consumer goodwill towards the next product. The latest trend is for reduction in the number of blockbuster drugs and pharmaceutical companies delvin g back into their former research to find potential missing new specialized drugs, .this can be seen clearly by the reduction in applications to the FDA showing ever reducing numbers of new drugs. Another complication that pharmaceutical companies must contend with is the ever-growing number of over-the-counter substitutes (OTCs) that the consumers choose to purchase as an alternative. Over a period of 20 years Naprosyn was widely prescribed as an arthritis remedy but now is available as an over-the-counter drug. A whole spectrum of drugs from arthritis to antihistamines are now available without prescription providing relief to customers but adding little to the economic bottom line of pharmaceutical companies that originally developed these drugs. Another complication in drug marketing is the force exerted by HMOs on doctors and what doctors prescribe .Generally the majority of HMOs are not big on covering high prescription costs for new medicines recently brought to market. The economics are easily understandable because it is not about a single client which needs a single drug but the numbers are multiplied by the potential hundreds of thousands. Therefore HMOs seek to be conservative. And because of that they create a potential customer roadblock for pharmaceutical companies with the new drug on the market at a very high price. Because of the HMO will not cove r the price then the customer must, which generally means the consumer settles for less than the newest product. managed care organizations (MCO), compared with 5 per cent of the US population covered in 1980. These MCOs typically provided full coverage for prescription drugs. But, because of their sheer mass, these institutions had considerable bargaining power with drug companies If present industry overview is taken into consideration then the global pharmaceutical market in 2010 is projected to grow 4 6% exceeding $825 billion. The global pharmaceutical market sales is expected to grow at a 4 7% compound annual growth rate (CAGR) through 2013. This industry growth is driven by stronger near-term growth in the US market and is based on the global macroeconomy, the changing combination of innovative and mature products apart from the rising influence of healthcare access and funding on market demand. Global pharmaceutical market value is expected to expand to $975+ billion by 2013. Different regions of the world will influence the pharmaceutical industry trends in different ways. http://www.da-group.co.uk/index.php?option=com_contentview=articleid=31%3Amicro-and-macro-environmentscatid=2%3Amarketing-lecturesItemid=3 CURRENT CHALLENGES FOR THE RESEARCH-BASED INDUSTRY To understand why â€Å"business as usual† is no longer an option for the research-based drug industry, it is worth considering some of the myriad challenges that drug companies currently face. At the top of the list is the upcoming onslaught of patent expirations of many highrevenue- generating branded medicines. Between 2009 and 2012, worldwide sales for these products will exceed $112 billion (Table 1). Included in this list are 36 blockbusters (drugs with annual sales of $1 billion or more). Some important examples include Singulair (montelukast), with more than $4 billion in annual sales (patent expiration in 2012); Plavix (clopidogrel), with more than $8 billion in annual sales (patent expiration in 2011); and Lipitor (atorvastatin), with an industry-leading $13.7 billion in annual sales (patent expiration in 2010). Given that only 3 in 10 new products, on average, generate revenues equal to or greater than average industry RD costs,1 the loss of patent protection on the se blockbusters represents a very real threat to the industrys ability to sustain its own growth. Without question, many of the large pharma mergers and acquisitions announced in 2009 reflect the industrys desire to avoid the imminent danger of the patent cliff, rather than an interest in enhancing RD capabilities or scope. The current environment for innovation presents formidable economic, regulatory, and political challenges for the research-based pharmaceutical industry. In particular, the growing time, cost, and risk related to drug development are stubborn obstacles to filling industry pipelines and boosting the output of new pharmaceutical and biological products. Presented here is a model of an innovation network. Although structures may vary, the innovation network offers the best mechanism to ensure viability and economic success for all sectors of the pharmaceutical and biotechnology industry, as well as the uninterrupted flow of innovative lifesaving and life-improving medicines for waiting patients. The Rise of Contract Research Organizations Clinical trials are administered by investigators at hospitals, academic institutions or managed sites. The investigators find and enroll healthy and symptomatic volunteers, each of whom is required to sign an informed consent acknowledging acceptance of the drug and its potential side effects. The testing protocol and informed consent form are monitored by Institutional Review Boards (IRBs) in the sites where the trials are conducted. In essence, the IRB acts as an ethics committee to ensure the safety of patients and volunteers. Once clinical trials are completed, the data are subjected to biostatistical analysis over a 6 to 12 month period.3 If the data yield promising results, the sponsor seeks final approval though a New Drug Application (NDA). The NDA must contain all scientific information the sponsor has gathered and typically fills 100,000 pages or more.4 During the review period, the FDA assesses the safety and effectiveness of th e drug, the manufacturing process, and the risk-benefit calculus.5 By law, the FDA has 180 days to either approve the application or notify the sponsor of the opportunity to request a hearing on the merits of the application.6 In practice, however, the FDA review process takes more than two years; in 1996, for example, the mean approval time for NDAs was 17.8 months, down from over 30 months during the late 1980s.7 Following approval, the FDA may require additional post-market research. Post-market surveillance regulations require the sponsor to collect and periodically report additional safety and efficacy data.8 In addition, the FDA may request further clinical research (Phase IV) to find new uses for the drug, test dosage formulations, compare the drug to competitors treatments, and assess long-term effects.9 Finally, pharmaceutical Conclusions A continuous call for ethical standards by pharmaceutical companies that market in the United States is often put aside because company marketing and business model of making profits matter more.(Pharmaceutical Drug Manufacturer, 2011). Brezis (2008) writes that the US public will lose out in the long run because the pharmaceutical companies are more focused on marketing and profits than about public health. Drug trial deaths still happen and have been described as a trade secret. It is not just one of the big pharmaceutical companies by Johnson Johnson, Merick and others whose own safety documents raise concerns that are buried in stacks of papers while marketing continues (Brezis, 2008). But this is offset by the ability of both the doctor and patient to use the Internet to search out the detailed information and become truly informed. Each of them can then make an informed decision about the benefits and potential drawbacks of using pharmaceuticals.

Anne Robert Jaques Turgot and His Relevance to the French Revolution :: essays research papers fc

Introduction Anne Robert Jaques Turgot, baron l' Aulne, was born in Paris on May 10, 1727 to a noble French family of Normandy. Following in the footsteps of his ancestors, who had furnished the state with numerous public officials, Turgot would achieve public renown as Intendent of Limoges and later as Controller General of all France. Although Turgot ended his public career in unfortunate circumstances, being dismissed by Louis XVI for ineffectiveness, his political theories became a major influence in the remaining years of the Old Regime. The depth of Turgot’s economic thought was not recognized at the time because it largely went against what the ruling aristocracy wanted to hear. His clairvoyance is much more fully noted in light of the last two centuries. Furthermore, Turgot was one of the King’s last controller-generals before the French Revolution ended the monarchy. When his political and economic ideals are considered against this backdrop their importance as well as thei r contradictory nature become apparent. Turgot's main contribution to economic theory is his Reflections on the Formation and Distribution of Riches. Apart from this short but highly systematic account of the nature of economic development, Turgot's other relevant writings are sparse and far from cohesive. Since this paper will consider his economics with regard to his political thought, only Turgot’s theories on the nature of government influence, free trade, and taxes will be examined. Furthermore, an explanation of Turgot’s theory on administration will be provided. In gaining an understanding of Turgot’s political and economic thought a powerful example of the problems that manifested themselves in the revolution is provided. Turgot was the model of an enlightened, reform-minded administrator and this may be glimpsed in the liberality of his economic ideas. However, while he certainly advised reforms in administration, they were simply intended so that the King could more effectively centralize pol itical power. Laissez-Faire and Free Trade: As a young man Turgot was very close to Claude Marie Vincent, the Marquis de Gournay. Vincent was not only a friend but also Turgot's mentor in economics and administration. It is in tribute to Vincent that after his death Turgot developed his ideas on laissez-faire government in a paper called, the "Elegy to Gournay" (1759). Within this paper Turgot condemns the foolishness of mercantilist regulation of industry while expounding the benefits of free domestic and foreign trade following from the presence of free exchange. In a detailed analysis of the market process, Turgot writes that self-interest is the prime mover in the market process and that in a free market the individual interest must always coincide with the general interest.

John Locke Leader of the Enlightenment Essay

John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. A ll three rightspertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Locke discusses the need for three natural rights, the right to property, life and liberty. All three rights pertained to equality and seeing as the Enlightenment Era revolved around individualism, his development and support of Natural Rights made him a great influence and role-model. Furthermore, John Locke was against the Divine Right of Kings and believed that there was no one true ruler that was chosen by god. He instead believed that the ruling force should be decided by the citizens of a country. This in turn allowed the citizens more liberty and thus more equality – everyone’s votes counted and each vote was equal. His belief in Natural rights also influenced many other movements and laws such as the French Revolution, the US Constitution, the American Declaration of Independence and The Social Contract. If it wasn’t for him and his literature, many leaders of the Enlightenment such as Voltaire wouldn’t have been inspired to come up with and share their ideas. John Locke’s influences on politics, equality and the other leaders of the Enlightenment were immense, thus making him one of the greatest leaders of The Enlightenment. John Locke has had a great impact on governments, other leaders and equality during the Enlightenment, thus making him the most influential leader of that era. Locke’s literature – specifically his book The Two Treatises of Government – was the key to many of his contributions. â€Å"By far the most influential writings emerged from the pen of scholar John Locke† (Powell, Jim). In this book, Loc.

Antibiotic Resistance In Bacteria Essays - Pharmaceuticals Policy

Antibiotic Resistance In Bacteria Essays - Pharmaceuticals Policy Antibiotic Resistance In Bacteria For about 50 years, antibiotics have been the answer to many bacterial infections. Antibiotics are chemical substances that are secreted by living things. Doctors prescribed these medicines to cure many diseases. During World War II, it treated one of the biggest killers during wartime - infected wounds. It was the beginning of the antibiotic era. But just when antibiotics were being mass produced, bacteria started to evolve and became resistant to these medicines. Antibiotic resistance can be the result of different things. One cause of resistance could be drug abuse. There are people who believe that when they get sick, antibiotics are the answer. The more times you use a drug, the more it will decrease the effect it has on you. That is because the bacteria has found a way to avoid the effects of that antibiotic. Another cause of resistance is the improper use of drugs. When patients feel that the symptoms of their disease have improved, they often stop taking the drug. Just because the symptoms have disappeared it does not mean the disease has gone away. Prescribed drugs should be taken until all the medicine is gone so the disease is completely finished. If it is not, then this will just give the bacteria some time to find a way to avoid the effects of the drug. One antibiotic that will always have a long lasting effect in history is penicillin. This was the first antibiotic ever to be discovered. Alexander Fleming was the person responsible for the discovery in 1928. In his laboratory, he noticed that in some of his bacteria colonies, that he was growing, were some clear spots. He realized that something had killed the bacteria in these clear spots, which ended up to be a fungus growth. He then discovered that inside this mold was a substance that killed bacteria. It was the antibiotic, penicillin. Penicillin became the most powerful germ-killer known at that time. Antibiotics kill disease-causing bacteria by interfering with their processes. Penicillin kills bacteria by attaching to their cell walls. Then it destroys part of the wall. The cell wall breaks apart and bacteria dies. After four years, when drug companies started to mass produce penicillin, in 1943, the first signs of penicillin-resistant bacteria started to show up. The first bacteria that fought penicillin was called Staphylococcus aureus. This bug is usually harmless but can cause an illness such as pneumonia. In 1967, another penicillin-resistant bacteria formed. It was called pneumococcus and it broke out in a small village in Papua New Guinea. Other penicillin resistant bacteria that formed are Enterococcus faecium and a new strain of gonorrhea. Antibiotic resistance can occur by a mutation of DNA in bacteria or DNA acquired from another bacteria that is drug-resistant through transformation. Penicillin-resistant bacteria can alter their cell walls so penicillin can not attach to it. The bacteria can also produce different enzymes that can take apart the antibiotic. Since antibiotics became so prosperous, all other strategies to fight bacterial diseases were put aside. Now since the effects of antibiotics are decreasing and antibiotic resistance is increasing, new research on how to battle bacteria is starting. Antibiotic resistance spreads fast but efforts are being made to slow it. Improving infection control, discovering new antibiotics, and taking drugs more appropriately are ways to prevent resistant bacteria from spreading. In developing nations, approaches are being made to control infections such as hand washing by health care people, and identifying drug resistant infections quickly to keep them away from others. The World Health Organization has began a global computer program that reports any outbreaks of drug-resistant bacterial infections. In the early 1900's, the discovery of penicillin began the antibiotic era. People thought they have finally won the battle with bacteria. But now since antibiotic resistance is increasing rapidly, new strategies must be developed to destroy these microbes. To many scientists the antibiotic era is over Bibliography Bylinsky, Gene. Sept. 5,1995. The new fight against killer microbes. Fortune. p. 74-76. Dixon, Bernard. March 17,1995. Return of the killer bugs. New Statesman & Society. p. 29-32. Levy, Stuart B. Jan. 15,1995. Dawn of the post-antibiotic era? Patient Care. p. 84-86. Lewis, Ricki. Sept. 1995. The rise of antibiotic-resistant infections. FDA Consumer. p. 11-15. Miller, Julie Ann. June 1995. Preparing for the postantibiotic era. BioScience. p. 384-392. an excellent news article summary, got me a 100, by strife007